CLINICAL AND THERAPEUTIC NUTRITION

1. Nutritional Intervention – Diet modifications
2. Special feeding methods in nutritional support
3. Significance of Anti inflammatory foods
4. Nutritional management of food allergies and food intolerances.

4.   Diet, nutrient and drug interaction

• Basic concept
• Effect of Nutrition on drugs
• Effect of drug on Nutritional status, food intake, digestion, absorption and metabolism of nutrient.

Drug and drug interaction

Incidence, etiology, metabolic changes, clinical manifestations, complications and dietary management for the following -                                                                                                                                

• Gastro-Intestinal Diseases and Disorders –Oesophagitis, Gastro Oesophageal Reflux Disorder (GERD), Hiatus Hernia, Dyspepsia, Gastritis, Diverticular disease, Peptic Ulcer, Malabsorption Syndrome
• (Celiac disease, Tropical sprue, Steatorrhoea, Lactose intolerance) Inflammatory Bowel Syndrome, Ulcerative Colitis, Short Bowel Syndrome.
• Liver, Gall bladder and Pancreatic diseases

a. Liver Diseases –Liver Cirrhosis, Hepatic Encephalopathy (HE)/ Hepatic Coma,

b. Pancreatic Diseases – Pancreatitis

c. Gall Bladder Diseases – Cholelithiasis, Cholecystitis, Cholecystectomy

Eating Disorders

Incidence, etiology, metabolic changes, clinical manifestations, complications and     dietary management for the following -

• Cardio vascular disease (CVD) – Dyslipideimia, Atherosclerosis, Hypertension (HT), Angina Pectoris, Myocardial Infarction (MI), Congestive Cardiac failure (CCF), Rheumatic Heart Disease (RHD) Prevention of CHD.
• Metabolic disorders - Diabetes Mellitus, Gout
• Renal Diseases – Glomerulonephritis (Acute and Chronic), Nephrotic Syndrome,   Nephrolithiasis (Renal calculi), Nephrosclerosis, Renal Failure (Acute and chronic), End Stage Renal Failure (ESRD), Dialysis (Haemodialysis and Peritoneal Dialysis), Kidney Transplantation.
• Cancer

Nutrition immunity and infection

Innate and adoptive immunity, primary and secondary lymphoid organs, cell mediated and humoral immunity, T and B lymphocytes, antibody  response, primary and secondary infection, role of nutrition in immune functions, immune aberration – HIV infection and AIDS. 

Nutrition and stress -Sress types, body’s response (endocrine and metabolic) to short term and long term stress. Role of nutrition in stress coping

• Surgery- pre operative and post operative nutritional care
• Burns –classification, dietary management and mode of feeding
• Trauma –physiological, metabolic and hormonal response to injury,dietary managemant

• Inborn errors of metabolism

• Disorders of Amino Acid metabolism – Phenylketonuria, hypertyrosinemia, hypervalinemia, hyperhistidinemia, hyperlysinemia, homocystinuria.
• Disorders of carbohydrate metabolism – Galactosemia, Pentosuria.
• Disorders of lipid metabolism – Hyperchylomicronemia, hypercholesterolemia – pure and mixed.

• Incidence, etiology, pathology. clinical manifestations, complications, dietary        management and counseling in Rheumatoid arthritis, osteoarthritis, osteoporosis
• Nutritional care of hospitalized patients - Hospital malnutrition, screening and nutritional assessment of critically ill patient