NUTRITIONAL BIOCHEMISTRY

Paper Code: 
DHSC 513 (A)
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

Course Objectives (COs):

This course will enable the students to –

  1. Understand the principles of biochemistry
  2. Apply the chemistry of major nutrients and physiologically important compounds
  3. Understand the biochemical process and systems as applicable to human nutrition
  4. Apply the knowledge in human nutrition and dietetics

Course Outcomes (COs):

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment

Strategies

  
 

The students will be able to –

CO201: Develop an understanding of the principles of biochemistry.

CO202: Outline the chemistry of major nutrients and physiologically important biomolecules. 

 CO203: Relate the biological processes and systems to biomolecules.

CO204: Compare the metabolism of macronutrients in our body

Approach in teaching:

Interactive Lectures, Discussion, assignments, power point presentations.

 

Learning activities for the students:

Self learning assignments, Seminar presentation

Class test, CA test, Semester end examinations, Quiz, Assignments, Presentation,

  

 

12.00
Unit I: 
Carbohydrates
  • Definitions, classification, structure, Physical and chemical properties of:
  • Monosaccharide’s -- glucose, fructose, galactose,
  • Disaccharides – maltose, lactose, sucrose
  • Polysaccharides – dextrin, starch, glycogen
12.00
Unit II: 
Proteins
  • Definition, classification, structure of amino acids
  •  Essential and non-essential amino acids
  •  Definition, classification, elementary knowledge of structure of proteins
  • Enzymes – Definition, classification, mechanism of enzyme action, specificity of enzymes and factors affecting enzyme activity.
12.00
Unit III: 
Lipids
  • Definitions and classification of lipids
  • Types and properties of fatty acids
  • Composition and properties of fats (hydrogenation, halogenation, iodine no., hydrolysis, saponification number, acid number and rancidity
  • Significance of acid value, iodine value and saponification value

 

12.00
Unit IV: 
Minerals & Vitamins
  • Minerals –Biochemical role of Calcium, Phosphorus, Iron, Iodine, Fluoride, Zinc and Selenium
  • Vitamins – Biochemical roleof fat – soluble vitamins – A, D, E, K and water soluble vitamins – B-complex (B1, B2, niacin, pyridoxine, folic acid, B12) and C.

 

12.00
  • Intermediary metabolism – Carbohydrates – Glycolysis, TCA cycle,   glycogenesis, glycogenolysis, gluconeogenesis, energetics of Glycolysis and TCA cycle.
  • Lipids – Beta oxidation of fatty acids and its energetics
  • Proteins – General reactions of Amino acid metabolism: deamination, transamination, decarboxylation and urea cycle.

 

Essential Readings: 
  • Satyanarayan U (2002) Biochemistry.Uppala author-publisher interlinks, Vijaywada
  • Harper, H.A. Review of Physiological Chemistry. Lange medical Library
  • Rama Rao, A.V.SS : A Text Book of Biochemistry L.K. and S. Publishers, Tanuka.

 

References: 
  • West, E.S. Todd W.R. Mason, H.S. and Van Bruggen J.T (1974) 4th Ed. Text Book of Biochemistry, Amerind Publishing Co. Pvt. Ltd.
  • Lehninger A.L., Nelson D.L. and Cox. M.M. (1993) 2nd Ed. Principles of Biochemistry CBS Publishers and Distributors.
  • Devlin T.M. (1986) 2nd Ed. Text Book of Biochemistry with Clinical Correlation, John Wiley and Sons.
  • Fruton J and Symond S. General Biochemistry, Asia Publishing House, Bombay.
  • Nagar, R and Nair, S. Biochemistry. Rajasthan Hinidi Granth Academy, Jaipur 2001.
  • Oser B.L. (1965) 14th Ed. Hawk’s Physiological Chemistry McGraw Hill Book Co.
  • Sharma Sheel, Practical Biochemistry. Classic Publishing House, Jaipur-Delhi (1993).
  • Stryu L. (1995) Biochemistry Freeman WH & Co.
  • Sundararaj, P and Siddhu A (1995) Qualitative tests and Quantitative Procedures in Biochemsitry.
  • Varley H. Gowenlock, A.H. and Bell, M (1980) 5th Ed. Practical and Clinical Chemistry Vol. I William Heinemann Medical Book Ltd.
  • William S, 16th Ed. JAOAC Official Methods of Analysis of the Association of Official Analytical Chemists.
  • White, A. Handar, P. Smith E.L. Stelten D.W. (1959) 2nd Ed. Principles of Biochemistry McGraw Hill Book Co.
  • Dutt, Debjani R. – How best to plan  and build your home – Pustak Mahal Delhi.
  • Sharma Sheel , Experiments and techniques in biochemistry, Galgotia Publishers , Daryaganj- New Delhi 

REFERENCE JOURNALS:  

  • Journal of Nutritional Biochemistry
  • Journal of Clinical Biochemistry and Nutrition
  • Annual Review of Biochemistry

 

E RESOURCES:

 

 

 

Academic Year: 
2023-2024
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