ADVANCE NUTRITIONAL BIOCHEMISTRY II

Paper Code: 
HFN 221
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

 

Course Objectives:

This course will enable the students to –

 

  • .       Understand the biochemical role of vitamins and minerals and their disorders and imbalances.
  • .  Understand toxicity in the body and role of antioxidants in detoxification of the body

 Course Learning Outcomes (COs):

 



Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment

Strategies

Paper Code

Paper Title

 

 

 

 

 

 

HFN 221

Advanced Nutritional Biochemistry -  II

(Theory)

 

 

 

 

 

The students will be able to –

COFN34: Develop skills in understanding the biochemistry of DNA and RNA and the application knowledge of purine and pyrimidine metabolism and their management.

 

COFN35: Develop skills in planning the diets as to consider the biochemical functions of various micronutrients

 

COFN36: Detoxification of various compounds and the knowledge of xenobiotics and its practical application for the management of various diseases. 

 

Approach in teaching:

Interactive Lectures, Discussion, Power Point Presentations, Informative videos, group discussion

 

Learning activities for the students:

Self learning assignments, Effective questions, presentations, Field trips

 

 

Quiz, Poster Presentations,

Power Point Presentations, Individual and group projects,

Open Book Test, Semester End Examination, discussion, demonstration

 

 

 

 

9.00
Unit I: 
  • Nucleic acid Chemistry
  • Structures of purines, pyrimidines, Nucleocides, Nucleotides,
  •  Metabolism of Purine and Pyrimidine,
  •  Disorders of purine metabolism
  • Composition, classification, structure and properties of DNA and RNA; functions of nucleic acids - DNA  replication and  RNA transcription
9.00
Unit II: 

Hormones

Definition, classification, mode of action, Chemistry and functions of Thyroxine, Insulin, Catecholamines

Disorders associated with the hormones

Antioxidants

Antioxidants and free radicals; role of O2 free radicals; production of O2 free radicals; physiological mechanisms to limit free radical damage; free radical in human pathology and disease.

 

9.00
Unit III: 

Vitamins

Classification and Biochemical role of vitamins –

  • Fat soluble vitamins A, D, E, K, C and B-complex.
  • Water soluble vitamins B1,B2,B3,B6,B12,Pantothenic acid,

 

 

9.00
Unit IV: 
  • Biochemical roles 0f
  • Macro minerals: Calcium, Phosporous, magnesium, sodium, potassium and chloride
  • Micro Minerals: Iron, copper, zinc, manganese, iodine, fluoride
  • Trace Minerals: Selenium, cobalt, chromium, vanadium, silicon, nickel

 

9.00
Unit V: 
  • Biochemical roles 0f
  • Macro minerals: Calcium, Phosporous, magnesium, sodium, potassium and chloride
  • Micro Minerals: Iron, copper, zinc, manganese, iodine, fluoride
  • Trace Minerals: Selenium, cobalt, chromium, vanadium, silicon, nickel

 

Essential Readings: 
  • Rao, K.R. (1986) Textbook of Biochemistry, III Edition. Prentice Hall of India Pvt. Ltd., New Delhi.
  • Murray, R.K. Granner, P.A. Mayes, V.W. Rodwell (1988) Harper’s Biochemistry. 21st Edition. Prentice Hall of Australia Pvt. Ltd.
  • Lehninger, A.L. (1987) Principles of Bio-chemistry – CBS Publishers and Distributors
  • West, E.S. Todd W.R. Mason, H.S. and Van Bruggen J.T (1974) 4th Ed. Text Book of Biochemistry, Amerind Publishing Co. Pvt. Ltd.
  • Harper, H.A. Review of Physiological Chemistry. Lange medical Library
  • White, A., Handler, P. and Smith, E.L. Principles of Biochemistry . W. B. Saunders Book Co. Philadelphia
References: 
  • Berg, Jeremy Mark, Tymoczko, John L and Stryer. (2002). Biochemistry 5th ed. New York. W.H. Freeman and Co.
  • Brody Tom. (2004). Nutritional Biochemistry 2nd ed. New Delhi. Elsevier/Reed. Elsevier. India Pvt. Ltd.
  • Chatterjee, M.N. Shinde and Rana. (2005). Textbook of Medical Biochemistry, 6th ed. New Delhi, Jaypee Brothers. Medical Publisher.
  •  Dandekar Sucheta P. (2002). Medical Biochemistry (Prep Manual for U.G.) 2nd ed. New Delhi B-1 Churchill Livingstone Pvt. Ltd.
  • Rastogi S.C. (1993). Biochemistry New Delhi, Tata McGraw Hill Publishing Co. Ltd.Definition, classification of lipids. Simple, Compound and derived
  • Kahn Conn, E.E. and Stump, P.K. Outlines of Biochemistry. Willey Eastern Pvt. Ltd. New Delhi
  • Stryer L. (1995) Biochemistry Freeman WH & Co.
  • Sundararaj, P and Siddhu A (1995) Qualitative tests and Quantitative Procedures in Biochemsitry.
  • Varley H. Gowenlock, A.H. and Bell, M (1980) 5th Ed. Practical and Clinical Chemistry Vol. I William Heinemann Medical Book Ltd.
Academic Year: 
2019-2020
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